Please use this identifier to cite or link to this item: https://hdl.handle.net/1/1748
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dc.contributor.authorClifford, Liam-
dc.contributor.otherLi, J.-
dc.contributor.otherRenaud, C.J.-
dc.contributor.otherFernando, S.L.-
dc.date.accessioned2020-02-03T02:27:51Z-
dc.date.available2020-02-03T02:27:51Z-
dc.date.issued2019-12-
dc.identifier.citation2019:2673947en
dc.identifier.issn2090-6897en
dc.identifier.urihttps://elibrary.cclhd.health.nsw.gov.au/cclhdjspui/handle/1/1748-
dc.description.abstractBackground: Microscopic polyangiitis (MPA) can manifest with atypical features such as pulmonary fibrosis and chronic obstructive pulmonary disease (COPD), which are atypical and unusual features of small vessel vasculitis. Case Presentation: This paper presents two patients with microscopic polyangiitis and respiratory symptoms attributable to atypical pulmonary manifestations. Pulmonary fibrosis was present in both cases, with COPD also present in one patient. Management involved methylprednisone, prednisone, and cyclophosphamide. The second patient also received azathioprine. Both patients responded well to immunosuppressive treatment; however, pulmonary fibrosis and COPD were refractory to immunosuppression. Conclusion: Pulmonary manifestations including pulmonary fibrosis, emphysema, and bronchiectasis are observed in MPA. Evaluation of MPA in unexplained cases should be performed to avoid delays in diagnosis and management. Patients who present with MPA with pulmonary manifestations may respond to treatment, but their pulmonary features demonstrate a refractory nature to such management.en
dc.description.sponsorshipMedicineen
dc.subjectDrug Therapyen
dc.subjectImmunologyen
dc.titleMicroscopic Polyangiitis with Pulmonary Fibrosis: An Often-Recognized Manifestation of the Diseaseen
dc.typeJournal Articleen
dc.identifier.doi10.1155/2019/2673947en
dc.description.pubmedurihttps://www.ncbi.nlm.nih.gov/pubmed/31976114en
dc.description.affiliatesCentral Coast Local Health Districten
dc.description.affiliatesGosford Hospitalen
dc.identifier.journaltitleCase reports in rheumatologyen
dc.type.studyortrialCase Series and Case Reportsen
dc.relation.orcidhttps://orcid.org/0000-0002-3933-4425en
dc.originaltypeTexten
item.openairetypeJournal Article-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.deptEndocrinology-
Appears in Collections:Health Service Research
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