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Title: Targeted Therapies for Microvascular Disease
Authors: Bland, Adam ;Chuah, Eunice ;Meere, William 
Affliation: Central Coast Local Health District
Gosford Hospital
Issue Date: Jan-2023
Source: 12(1):131-139
Journal title: Interventional Cardiology Clinics
Department: Cardiology
Abstract: Coronary microvascular dysfunction (CMD) is a common cause of ischemia but no obstructive coronary artery disease that results in an inability of the coronary microvasculature to meet myocardial oxygen demand. CMD is challenging to diagnose and manage due to a lack of mechanistic research and targeted therapy. Recent evidence suggests we can improved patient outcomes by stratifying antianginal therapies according to the diagnosis revealed by invasive assessment of the coronary microcirculation. This review article appraises the evidence for management of CMD, which includes treatment of cardiovascular risk, antianginal therapy and therapy for atherosclerosis.
DOI: 10.1016/j.iccl.2022.09.011
Publicaton type: Journal Article
Keywords: Cardiology
Cardiovascular Disease
Heart Disease
Appears in Collections:Cardiology

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