Please use this identifier to cite or link to this item:
https://hdl.handle.net/1/2706
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DC Field | Value | Language |
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dc.contributor.author | Bland, Adam | - |
dc.contributor.author | Meere, William | - |
dc.contributor.author | Mikhail, Philopatir | - |
dc.contributor.author | Chuah, Eunice | - |
dc.contributor.author | Redwood, Eleanor | - |
dc.contributor.author | Ferreira, David | - |
dc.contributor.author | Howden, Nicklas | - |
dc.contributor.author | Perkovic, Adam | - |
dc.contributor.author | Saunders, Samantha | - |
dc.contributor.author | Kelty, Amy | - |
dc.contributor.author | Kull, Anthony | - |
dc.contributor.author | Hill, Andrew | - |
dc.contributor.author | Spina, Roberto | - |
dc.contributor.author | Sarathy, Kiran | - |
dc.contributor.author | May, Austin N | - |
dc.contributor.author | Parkinson, Michael | - |
dc.contributor.author | Ishak, Mark | - |
dc.contributor.author | Collins, Nicholas | - |
dc.contributor.author | Boyle, Andrew | - |
dc.contributor.author | William, Maged | - |
dc.contributor.author | Jeyaprakashk, Prajith | - |
dc.contributor.author | Ford, Tom | - |
dc.date.accessioned | 2024-09-04T01:46:06Z | - |
dc.date.available | 2024-09-04T01:46:06Z | - |
dc.date.issued | 2024-08-31 | - |
dc.identifier.citation | Online ahead of print | en |
dc.identifier.uri | https://hdl.handle.net/1/2706 | - |
dc.description.abstract | Background: The 1.5mm 'Baby J' hydrophilic narrow J tipped wire is a development of the standard 0.035" 3mm J tipped peripheral guidewire, designed to improve efficiency of transradial coronary procedures by safely navigating small caliber radial arteries to the aorta. There is currently a lack of evidence comparing the procedural success and safety of different peripheral guidewires used in transradial cardiac procedures. We compared the efficacy and safety of a narrow J tipped hydrophilic 0.035" wire (intervention - Radifocus™ 'Baby J' guidewire, TERUMO Co., Tokyo, Japan). versus standard fixed core (FC) 0.035" J wire (control). Methods: Investigator initiated, blinded, Australian, multicenter randomized trial in patients undergoing clinically indicated coronary angiography and/or PCI. Randomized 1:1 via sealed envelope method to use either the control or the intervention guidewire. The primary endpoint (technical success) was defined as gaining aortic root access with the randomized guidewire. Results: 330 patients were randomized between October 2022 - June 2023 (median age 69 years, 36% female, BMI 29 kg/m²). The primary endpoint was achieved more frequently in the intervention group [96% v 84%; mean difference 12% (95% CI 5.7-18.3); p<0.001]. Women assigned to the control wire experienced a higher failure rate compared to men (31% v 8% in men; p<0.001). Fluoroscopy time was significantly shorter in the baby J group (median 344 versus 491 seconds; p=0.024). The main mechanisms of failure using the control wire were radial artery spasm (15/26; 57%) and subclavian tortuosity (5/26; 19.2%). There were no differences in overall procedure times, MACE, or vascular complications between guidewires. Conclusions: A narrow 1.5mm J tipped hydrophilic guidewire resulted in greater technical success and reduced fluoroscopy time compared to the standard 3mm J tip non-hydrophilic guidewire. The guidewire is safe and demonstrated key incremental benefits for the trans-radial approach particularly in women. | en |
dc.description.sponsorship | Cardiology | en |
dc.subject | Cardiology | en |
dc.subject | Cardiovascular Disease | en |
dc.title | Enhancing Guidewire Efficacy for Trans-radial Access: The EAGER Randomized Controlled Trial | en |
dc.type | Journal Article | en |
dc.description.pubmeduri | https://pubmed.ncbi.nlm.nih.gov/39215512 | en |
dc.description.affiliates | Central Coast Local Health District | en |
dc.description.affiliates | Gosford Hospital | en |
dc.identifier.journaltitle | Circulation. Cardiovascular Interventions | en |
dc.type.studyortrial | Randomized Controlled Clinical Trial/Controlled Clinical Trial | en |
dc.type.content | Text | en |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.openairetype | Journal Article | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Obstetrics & Gynaecology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
crisitem.author.dept | Cardiology | - |
Appears in Collections: | Cardiology |
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