Please use this identifier to cite or link to this item: https://hdl.handle.net/1/3029
Authors: Goonetilleke, Neil ;Howden, Nicklas ;Rogers, James 
Affliation: Central Coast Local Health District
Gosford Hospital
Issue Date: 1-Aug-2025
Department: Cardiology
Abstract: Background: Positron Emission Tomography (PET) with Computed Tomography (CT) is part of the diagnostic tools for infective endocarditis. Non-infected peri-valvular 18F-Flurodeoxyglucose (18F-FDG) uptake has been previously demonstrated in aortic metallic valves up to 52 weeks following implantation, with little known regarding chronic uptake. We present a case demonstrating increased 18F-FDG 30 years following metallic aortic and mitral valve replacement. Case: A 63-year-old male was admitted with a 4-day history of fevers, chills, rigors and delirium. There was no recent focus apart from a dental extraction 5 months prior. He has a cardiac background of metallic aortic and mitral replacement in 1994 due to rheumatic valve disease and a defibrillator implanted in 2021 following a VF arrest with normal coronaries. Blood cultures upon admission revealed Staphylococcus haemolyticis and a transoesphageal echocardiogram (TOE) showed no valvular abnormalities but did reveal a vegetation on the right ventricular lead following a negative transthoracic echocardiogram. Whole body PET 3 weeks following lead extraction revealed a mild uptake associated with the annulus of the aortic and mitral valvular replacement. A repeat TOE did not show any valvular vegetations. Under guidance from infectious-disease he completed 6 weeks of flucloxacillin and benzyl-penicillin. Surveillance blood-cultures were negative over a 3-month period and had recovered to baseline. Conclusion(s): This case highlights for the first known time that chronic FDG uptake can be observed for up to 30 years following AVR and MVR in non-infected prosthetic valves. Copyright © 2025
URI: https://hdl.handle.net/1/3029
Publicaton type: Conference Abstract
Keywords: Cardiology
Heart Disease
Appears in Collections:Health Service Research

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