Please use this identifier to cite or link to this item: https://hdl.handle.net/1/1372
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dc.contributor.authorForsyth, Cecily Jen
dc.contributor.otherSmith, A.en
dc.contributor.otherHeaps, L.S.en
dc.contributor.otherSharma, P.en
dc.contributor.otherJarvis, A.en
dc.date.accessioned2019-04-29T06:08:45Zen
dc.date.available2019-04-29T06:08:45Zen
dc.date.issued2001-10en
dc.identifier.citationVolume 130, Issue 1, pp. 29 - 32en
dc.identifier.issn0165-4608en
dc.identifier.urihttps://elibrary.cclhd.health.nsw.gov.au/cclhdjspui/handle/1/1372en
dc.description.abstractA 66-year-old man with a myelodysplastic syndrome transforming to acute myeloid leukemia showed a complex abnormal karyotype on bone marrow aspirate. An unbalanced dicentric translocation with a very long der(11) long arm-dic(11;19)(q25;p13.4)-was present. Fluorescence in situ hybridization studies utilised paints for chromosomes 11 and 19 as well as the locus specific probe MLL, localised to 11q23. The abnormal chromosome 11q contained 6 copies of intact MLL and 6 copies of chromosome 19 (unidentified) sequences. To our knowledge, gene co-amplification of chromosomes 11 and 19 sequences has not been reported before.en
dc.subjectHaematologyen
dc.subjectHematologyen
dc.subjectLeukaemiaen
dc.subjectLeukemiaen
dc.titleAbnormal dicentric chromosome with co-amplification of sequences from chromosomes 11 and 19: a novel rearrangement in a patient with myelodysplastic syndrome transforming to acute myeloid leukemiaen
dc.typeJournal Articleen
dc.description.pubmedurihttps://www.ncbi.nlm.nih.gov/pubmed/11672770en
dc.identifier.journaltitleCancer Genetics and Cytogeneticsen
dc.type.studyortrialCase Series and Case Reportsen
dc.relation.orcidhttps://orcid.org/0000-0002-9108-3088en
dc.originaltypeTexten
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
crisitem.author.deptHaematology-
Appears in Collections:Haematology
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