Please use this identifier to cite or link to this item:
https://hdl.handle.net/1/1372
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Forsyth, Cecily J | en |
dc.contributor.other | Smith, A. | en |
dc.contributor.other | Heaps, L.S. | en |
dc.contributor.other | Sharma, P. | en |
dc.contributor.other | Jarvis, A. | en |
dc.date.accessioned | 2019-04-29T06:08:45Z | en |
dc.date.available | 2019-04-29T06:08:45Z | en |
dc.date.issued | 2001-10 | en |
dc.identifier.citation | Volume 130, Issue 1, pp. 29 - 32 | en |
dc.identifier.issn | 0165-4608 | en |
dc.identifier.uri | https://elibrary.cclhd.health.nsw.gov.au/cclhdjspui/handle/1/1372 | en |
dc.description.abstract | A 66-year-old man with a myelodysplastic syndrome transforming to acute myeloid leukemia showed a complex abnormal karyotype on bone marrow aspirate. An unbalanced dicentric translocation with a very long der(11) long arm-dic(11;19)(q25;p13.4)-was present. Fluorescence in situ hybridization studies utilised paints for chromosomes 11 and 19 as well as the locus specific probe MLL, localised to 11q23. The abnormal chromosome 11q contained 6 copies of intact MLL and 6 copies of chromosome 19 (unidentified) sequences. To our knowledge, gene co-amplification of chromosomes 11 and 19 sequences has not been reported before. | en |
dc.subject | Haematology | en |
dc.subject | Hematology | en |
dc.subject | Leukaemia | en |
dc.subject | Leukemia | en |
dc.title | Abnormal dicentric chromosome with co-amplification of sequences from chromosomes 11 and 19: a novel rearrangement in a patient with myelodysplastic syndrome transforming to acute myeloid leukemia | en |
dc.type | Journal Article | en |
dc.description.pubmeduri | https://www.ncbi.nlm.nih.gov/pubmed/11672770 | en |
dc.identifier.journaltitle | Cancer Genetics and Cytogenetics | en |
dc.type.studyortrial | Case Series and Case Reports | en |
dc.relation.orcid | https://orcid.org/0000-0002-9108-3088 | en |
dc.originaltype | Text | en |
item.grantfulltext | none | - |
item.fulltext | No Fulltext | - |
item.cerifentitytype | Publications | - |
item.openairetype | Journal Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
Appears in Collections: | Haematology |
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