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|Title:||Dopamine dysregulation syndrome in non-Parkinson's disease patients: a systematic review||Authors:||Cartoon, Jodi ;Ramalingam, Jothi||Affliation:||Central Coast Local Health District
|Issue Date:||Apr-2019||Source:||27(5):456-461||Journal title:||Australasian Psychiatry||Department:||Psychiatry||Abstract:||OBJECTIVES: To explore the presence of dopamine dysregulation syndrome in non-Parkinson's disease patients receiving dopamine replacement therapy. METHODS: Electronic searches were conducted of Medline, Embase, PsycINFO and PreMedline to capture articles related to dopamine misuse or factitious disorder combined with the presence of dopamine replacement therapy or a non-Parkinson's disease population. In total, 430 articles were reviewed and studies that addressed dopamine dysregulation syndrome in non-Parkinson's disease patients were included. RESULTS: Nine case reports were identified. CONCLUSIONS: The pathophysiology underlying dopamine dysregulation syndrome has been thoroughly explored with numerous mechanisms posited. What remains unclear is whether dopamine dysregulation syndrome is a phenomenon specific to Parkinson's disease, as indicated in the proposed diagnostic criteria. A more useful predictor of susceptibility to dopamine dysregulation syndrome may be temperamental traits such as novelty seeking and impulsivity, which overlap with predisposing factors for an addiction disorder.||URI:||https://elibrary.cclhd.health.nsw.gov.au/cclhdjspui/handle/1/1480||DOI:||10.1177/1039856219839476||Pubmed:||https://www.ncbi.nlm.nih.gov/pubmed/31032624||ISSN:||1039-8562||Publicaton type:||Journal Article||Keywords:||Neurology
|Appears in Collections:||Health Service Research|
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