Please use this identifier to cite or link to this item:
|Title:||Randomised controlled trial (RCT) of daily aerobic exercise for inpatient cannabis withdrawal: A study protocol||Authors:||Murnion, Bridin ;Allsop, D.J.;Rooney, K.;Arnold, J.C.;Bhardwaj, A.K.;Bruno, R.;Bartlett, D.J.;Montebello, M.;Arkell, T.;Richards, E.;Gugusheff, J.||Affliation:||Central Coast Local Health District||Issue Date:||Oct-2017||Source:||13:57-67||Journal title:||Mental Health and Physical Activity||Department:||Drug & Alcohol||Abstract:||Background and aims: Cannabis withdrawal is thought to be a major contributor to relapse to cannabis use and is now included in the DSM-5. Aerobic exercise relieves withdrawal symptoms from tobacco and other drugs, but has yet to be tested in cannabis users. Methods: A prospective, single blind, parallel-group RCT comparing daily aerobic exercise to a control stretching intervention. Setting: A seven-day inpatient hospital admission, with follow-up at 28 days’ post-discharge. Participants: The study population will be 80 cannabis dependent adults seeking assistance with cannabis withdrawal. Intervention and comparator: Participants in the Intervention group will undergo 35 min of aerobic exercise daily, at 60% of their VO2 Max, on an exercise bicycle. The Control group will participate in a structured non-aerobic daily stretching routine for 35 min daily. Both groups receive treatment as usual in the withdrawal management unit of the hospital. Measurements: The primary outcome measure is the severity of cannabis withdrawal symptoms assessed daily using the Cannabis Withdrawal Scale and the Marijuana Cravings Questionnaire – pre and post exercise, across the week. Mechanisms by which exercise may affect cannabis withdrawal will be assessed by analysis of endogenous cannabinoids, and plasma and urine cannabinoid levels. Discussion: This is the first RCT of aerobic exercise for cannabis dependence that has a valid control group to aid in interpretation of findings. Should the intervention prove effective, it would give empirical support to an inexpensive and accessible treatment approach for drug withdrawal management.||URI:||https://elibrary.cclhd.health.nsw.gov.au/cclhdjspui/handle/1/1641||DOI:||10.1016/j.mhpa.2017.06.002||ISSN:||1755-2966||Publicaton type:||Journal Article||Keywords:||Drug and Alcohol||Study or Trial:||Randomized Controlled Clinical Trial/Controlled Clinical Trial|
|Appears in Collections:||Health Service Research|
Show full item record
checked on Jan 27, 2023
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.