Please use this identifier to cite or link to this item: https://hdl.handle.net/1/1954
Title: Can patient symptoms reliably predict major oesophageal motility disorders assessed by conventional water perfusion manometry?
Authors: Hamer, Peter W ;Stranz, C.;Watkinson, T.;Cross, A.;Roberts, R.
Affliation: Central Coast Local Health District
Issue Date: Mar-2021
Source: 134(1531):91-100
Journal title: The New Zealand Medical Journal
Department: General Surgery
Abstract: AIM: This study aimed to determine whether symptoms can reliably predict a major disorder of oesophageal motility as assessed by conventional water perfusion manometry. METHODS: Data from patients who underwent conventional water perfusion oesophageal manometry and a pre-manometry questionnaire between October 1998 and August 2018 were extracted from a database. Clinical features (dysphagia, chest pain, regurgitation, dysphagia to a bread challenge) and combinations of these clinical features were compared to manometric diagnoses. RESULTS: Data from 546 patients were analysed. Thirty-three (6%) patients had a major disorder of motility, and 513 (94%) had normal manometry or a minor disorder of motility. 'Any dysphagia' (dysphagia as a symptom or dysphagia to a bread challenge) or 'chest pain' was experienced by all patients with a major disorder of motility and 435 of 513 patients with normal manometry or a minor disorder of motility (p=0.009). Sensitivity was 100%, and specificity was 15%, in identifying patients with a major disorder of motility using symptom combinations and a bread challenge. CONCLUSION: Symptoms and provoked dysphagia to bread were able to predict patients with a major disorder of oesophageal motility with a sensitivity of 100%. However, as specificity was 15%, confirmation with manometry is indicated if possible.
URI: https://elibrary.cclhd.health.nsw.gov.au/cclhdjspui/handle/1/1954
Pubmed: https://pubmed.ncbi.nlm.nih.gov/33767490/
ISSN: 0028-8446
Publicaton type: Journal Article
Keywords: Gastrointestinal Tract
Appears in Collections:Gastroenterology

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