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Title: Monoclonal B-cell Lymphocytosis - a review of diagnostic criteria, biology, natural history, and clinical management
Authors: Tang, Catherine ;Shen, Yandong;Soosapilla, Asha;Mulligan, Stephen P
Affliation: Central Coast Local Health District
Gosford Hospital
Issue Date: 29-Jun-2022
Source: Online ahead of print
Journal title: Leukemia and Lymphoma
Department: Haematology
Abstract: Since first described almost two decades ago, there has been significant evolution in our definition and understanding of the biology and implications of monoclonal B-cell lymphocytosis (MBL). This review provides an overview of the definition, classification, biology, and natural history of MBL, mainly focused on the dominant CLL-like phenotype form of MBL. The increasingly recognized implications of MBL with respect to immune dysfunction are discussed, particularly in view of the COVID-19 pandemic, along with management recommendations for MBL in the clinic.
DOI: 10.1080/10428194.2022.2092857
Publicaton type: Journal Article
Keywords: Leukaemia
Study or Trial: Reviews/Systematic Reviews
Appears in Collections:Haematology

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