Please use this identifier to cite or link to this item: https://hdl.handle.net/1/1761
Title: Stage IV choriocarcinoma in a 47-year-old-woman 12 years after her last known pregnancy: A case report
Authors: Kumar, Molly ;McArthur, Seamus 
Affliation: Central Coast Local Health District
Gosford Hospital
Issue Date: Jan-2020
Source: 26:e00180
Journal title: Case Reports in Women's Health
Department: Obstetrics & Gynaecology
Abstract: Introduction: Choriocarcinoma is a rare, invasive, gestational trophoblastic disease that secretes high levels of beta human chorionic gonadotropin (BhCG) and is thought to affect 1 in 40,000 pregnancies. We present a rare case of metastatic choriocarcinoma. Case presentation: A 47-year-old woman presented with shortness of breath, anemia and an elevated serum BhCG level. Her most recent known pregnancy was 12 years previously. Following investigation, she was found to have FIGO stage IV choriocarcinoma with brain metastasis, despite having not experienced any abnormal vaginal bleeding. She was treated with chemotherapy; her treatment was complicated by neutropenic sepsis and a visceral perforation. The patient went into remission and received long-term follow-up. Discussion(s): It is unclear in this case whether the disease occurred following a pregnancy 12 years previously and was never detected or whether it was due to a recent unknown pregnancy or a non-gestational cause. Increased awareness of this condition will allow timely diagnosis, prompt management and improved prognosis. Following diagnosis, determination of BhCG levels is essential for monitoring and guiding treatment and a multidisciplinary approach should be taken towards care. Copyright © 2020 The Authors
URI: https://elibrary.cclhd.health.nsw.gov.au/cclhdjspui/handle/1/1761
DOI: 10.1016/j.crwh.2020.e00180
Pubmed: https://www.ncbi.nlm.nih.gov/pubmed/32095433
ISSN: 2214-9112
Publicaton type: Journal Article
Keywords: Cancer
Gynaecology
Gynecology
Study or Trial: Case Series and Case Reports
Appears in Collections:Oncology / Cancer

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