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Title: Syphilitic meningitis presenting with multiple cranial neuropathies
Authors: Sturm, Jonathan ;Chu, M.;Kumar, S.
Affliation: Central Coast Local Health District
Gosford Hospital
Issue Date: Jun-2021
Source: 14(6):e241765
Journal title: BMJ Case Reports
Department: Neurology
Abstract: Syphilis is increasingly prevalent in the community. The protean manifestations of neurosyphilis make the recognition, diagnosis and early initiation of treatment challenging. We report a case of early syphilitic meningitis presenting with multiple cranial neuropathies. Cerebrospinal fluid (CSF) examination was inflammatory with predominant lymphocytosis. The patient was diagnosed with neurosyphilis based on serum as well as CSF testing. Intravenous benzylpenicillin treatment resulted in rapid improvement of neurological symptoms. Neurosyphilis should be considered in immunocompetent patients presenting with multiple cranial neuropathies, or isolated cranial neuropathies without vascular risk factors.
DOI: 10.1136/bcr-2021-241765
ISSN: 1757-790x
Publicaton type: Journal Article
Keywords: Neurology
Drug Therapy
Study or Trial: Case Series and Case Reports
Appears in Collections:Neurology

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