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Title: International Hand Function Study Following Distal Radial Access: The RATATOUILLE Study
Authors: Ford, Tom ;Sgueglia, G.A.;Hassan, A.;Harb, S.;Koliastasis, L.;Milkas, A.;Zappi, D.M.;Navarro Lecaro, A.;Ionescu, E.;Rankin, S.;Said, C.F.;Kuiper, B.;Kiemeneij, F.
Affliation: Central Coast Local Health District
Gosford Hospital
Issue Date: May-2022
Source: 15(12):1205-1215
Journal title: JACC. Cardiovascular Interventions
Department: Cardiology
Abstract: OBJECTIVES: The study sought to comprehensively evaluate hand function in patients undergoing DRA. BACKGROUND: Distal radial access (DRA) has been proposed to improve procedure ergonomics and favor radial artery patency. Although promising data, nothing is known on evolving hand function after DRA. METHODS: Real-world patients undergoing DRA undertook a thorough multimodality assessment of hand function implementing multidomain questionnaires (Disabilities of the Arm, Shoulder and Hand and Levine-Katz), and motor (pinch grip test) and sensory (Semmes-Weinstein monofilaments test) examinations of both hands. All assessments were performed at pre-procedural baseline and planned at 1-, 6-, and 12-month follow-up (FU). Adverse clinical and procedural events were documented too. RESULTS: Data of 313 patients (220 men, 66 ± 10 years) from 9 international centers were analyzed. The Disabilities of the Arm, Shoulder and Hand and the Levine-Katz scores slightly improved from baseline to FU (P = 0.008 and P = 0.029, respectively). Pinch strength mildly improved from baseline to FU (P < 0.001 for both the left and right hands). Similarly, touch pressure threshold appeared to faintly improve in both the left and right hands (P < 0.012 for all the sites). For both motor and sensory function tests, comparable findings were found for the DRA hand and the contralateral one, with no significant differences between them. Repeated assessment of all tests over all FU time points similarly showed lack of worsening hand function. Access-related adverse events included 19 harmless bleedings and 3 forearm radial artery and 3 distal radial artery occlusions. None affected hand function at FU. CONCLUSIONS: In a systematic multidimensional assessment, DRA was not associated with hand function impairment. Moreover, DRA emerges as a safe alternative vascular access.
DOI: 10.1016/j.jcin.2022.04.023
ISSN: 1936-8798
Publicaton type: Journal Article
Keywords: Vascular Access
Appears in Collections:Cardiology

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