Please use this identifier to cite or link to this item: https://hdl.handle.net/1/841
Title: Synchronous or metachronous lymphoma and metastatic cutaneous squamous cell carcinoma in the head and neck region: a diagnostic and management dilemma
Authors: Kader, Imran ;Shashinder, Singh ;Wylie, Brenton ;Sundaresan, Purnima ;Leavers;Chi;Leavers, B.;Chi, K-K.
Affliation: Central Coast Local Health District
Gosford Hospital
The University of Newcastle
Issue Date: Jul-2016
Source: 130 Suppl 4:S45-9
Journal title: Journal of Laryngology and Otology
Department: Otolaryngology–Head & Neck Surgery
Abstract: OBJECTIVE: To review our experience of managing patients with a dual diagnosis of metastatic cutaneous squamous cell carcinoma in the head and neck region and low-grade non-Hodgkin lymphoma. The secondary aim was to evaluate the utility of 18F-fluorodeoxyglucose positron emission tomography during diagnosis. METHODS: Patients diagnosed with metastatic cutaneous squamous cell carcinoma of the head and neck and low-grade non-Hodgkin lymphoma, in a five-year period, were identified. Patient, tumour and treatment characteristics were identified. 18F-fluorodeoxyglucose positron emission tomography imaging was reviewed and correlated with histopathology findings. RESULTS: Eight patients were identified. There was a delay in diagnosis of metastatic squamous cell carcinoma in two patients. 18F-fluorodeoxyglucose positron emission tomography differentiated metastatic squamous cell carcinoma from low-grade non-Hodgkin lymphoma with a sensitivity of 88.2 per cent and a specificity of 94.7 per cent. In 38 per cent of patients, compromises in management had to be made. CONCLUSION: The management of metastatic squamous cell carcinoma can be challenging in patients with low-grade non-Hodgkin lymphoma. 18F-fluorodeoxyglucose positron emission tomography can be useful in the diagnosis of metastatic squamous cell carcinoma in patients with low-grade non-Hodgkin lymphoma
URI: https://elibrary.cclhd.health.nsw.gov.au/cclhdjspui/handle/1/841
DOI: 10.1017/S002221511600832X
Pubmed: http://www.ncbi.nlm.nih.gov/pubmed/27488337
ISSN: 0022-2151
Publicaton type: Journal Article
Keywords: Cancer
Appears in Collections:Oncology / Cancer

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