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|Title:||Synchronous or metachronous lymphoma and metastatic cutaneous squamous cell carcinoma in the head and neck region: a diagnostic and management dilemma||Authors:||Kader, Imran ;Shashinder, Singh ;Wylie, Brenton ;Sundaresan, Purnima ;Leavers;Chi;Leavers, B.;Chi, K-K.||Affliation:||Central Coast Local Health District
The University of Newcastle
|Issue Date:||Jul-2016||Source:||130 Suppl 4:S45-9||Journal title:||Journal of Laryngology and Otology||Department:||Otolaryngology–Head & Neck Surgery||Abstract:||OBJECTIVE: To review our experience of managing patients with a dual diagnosis of metastatic cutaneous squamous cell carcinoma in the head and neck region and low-grade non-Hodgkin lymphoma. The secondary aim was to evaluate the utility of 18F-fluorodeoxyglucose positron emission tomography during diagnosis. METHODS: Patients diagnosed with metastatic cutaneous squamous cell carcinoma of the head and neck and low-grade non-Hodgkin lymphoma, in a five-year period, were identified. Patient, tumour and treatment characteristics were identified. 18F-fluorodeoxyglucose positron emission tomography imaging was reviewed and correlated with histopathology findings. RESULTS: Eight patients were identified. There was a delay in diagnosis of metastatic squamous cell carcinoma in two patients. 18F-fluorodeoxyglucose positron emission tomography differentiated metastatic squamous cell carcinoma from low-grade non-Hodgkin lymphoma with a sensitivity of 88.2 per cent and a specificity of 94.7 per cent. In 38 per cent of patients, compromises in management had to be made. CONCLUSION: The management of metastatic squamous cell carcinoma can be challenging in patients with low-grade non-Hodgkin lymphoma. 18F-fluorodeoxyglucose positron emission tomography can be useful in the diagnosis of metastatic squamous cell carcinoma in patients with low-grade non-Hodgkin lymphoma||URI:||https://elibrary.cclhd.health.nsw.gov.au/cclhdjspui/handle/1/841||DOI:||10.1017/S002221511600832X||Pubmed:||http://www.ncbi.nlm.nih.gov/pubmed/27488337||ISSN:||0022-2151||Publicaton type:||Journal Article||Keywords:||Cancer|
|Appears in Collections:||Oncology / Cancer|
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