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https://hdl.handle.net/1/1321
Title: | Quality of life after stroke: the North East Melbourne Stroke Incidence Study (NEMESIS) | Authors: | Sturm, Jonathan ;Donnan, G.A.;Dewey, H.M.;Macdonell, R.A.;Gilligan, A.K.;Srikanth, V.K.;Thrift, A.G. | Issue Date: | Oct-2004 | Source: | Volume 35, Issue 10, pp. 2340 -2345 | Journal title: | Stroke | Abstract: | BACKGROUND AND PURPOSE: Health-related quality of life (HRQoL) data are scarce from unselected populations. The aims were to assess HRQoL at 2 years poststroke, to identify determinants of HRQoL in stroke survivors, and to identify predictors at stroke onset of subsequent HRQoL. METHODS: All first-ever cases of stroke in a population of 306 631 over a 1-year period were assessed. Stroke severity, comorbidity, and demographic information were recorded. Two-year poststroke HRQoL was assessed using the Assessment of Quality of Life (AQoL) instrument (deceased patients score=0). Handicap, disability, physical impairment, depression, anxiety, living arrangements, and recurrent stroke at 2 years were documented. If necessary, proxy assessments were obtained, except for mood. Linear regression analyses were performed to identify factors independently associated with HRQoL. RESULTS: Of 266 incident cases alive at 2 years, 225 (85%) were assessed. The mean AQoL utility score for all survivors was 0.47 (95% CI, 0.42 to 0.52). Almost 25% of survivors had a score of < or =0.1. The independent determinants of HRQoL in survivors were handicap, physical impairment, anxiety and depression, disability, institutionalization, dementia, and age. The factors present at stroke onset that independently predicted HRQoL at 2 years poststroke were age, female sex, initial NIHSS score, neglect, and low socioeconomic status. CONCLUSIONS: A substantial proportion of stroke survivors have very poor HRQoL. Interventions targeting handicap and mood have the potential to improve HRQoL independently of physical impairment and disability. | URI: | https://elibrary.cclhd.health.nsw.gov.au/cclhdjspui/handle/1/1321 | DOI: | 10.1161/01.STR.0000141977.18520.3b | Pubmed: | https://www.ncbi.nlm.nih.gov/pubmed/15331799 | ISSN: | 0039-2499 | Publicaton type: | Journal Article | Keywords: | Neurology Stroke |
Appears in Collections: | Neurology |
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