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Title: Radiotherapy for node-positive prostate cancer: 2019 Recommendations of the Australian and New Zealand Radiation Oncology Genito-Urinary group
Authors: Lieng, Hester ;Kneebone, Andrew ;Hayden, A.J.;Christie, D.R.H.;Davis, B.J.;Eade, Thomas ;Emmett, L.;Holt, T.;Hruby, G.;Pryor, D.;Sidhom, M.;Skala, M.;Yaxley, J.;Shakespeare, T.P.
Affliation: Central Coast Local Health District
Gosford Hospital
Issue Date: Jun-2019
Source: 140:68-75
Journal title: Radiotherapy and Oncology
Department: Central Coast Cancer Centre
Abstract: The management of node-positive prostate cancer is highly variable, with both locoregional and systemic treatment options available. With the increasing use of novel imaging techniques such as PSMA-PET and MRI, combined with the increasing use of surgery for high-risk prostate cancer, clinical and pathological regional nodal disease is being detected at a higher rate and at an earlier stage than previously. This creates a window for a potentially curative management approach. The role of radiotherapy including optimal radiation target volumes and dose, as well as the timing and duration of accompanying systemic therapy remains uncertain. At a workshop in 2017, the Australian and New Zealand Faculty of Radiation Oncology Genito-Urinary Group (FROGG) identified variations in the management of node-positive prostate cancer identified on primary staging or on histopathology at radical prostatectomy. FROGG reviewed the literature and developed a set of evidence-based recommendations on the appropriate investigation and management of clinically and pathologically node-positive prostate cancer. These recommendations encompass imaging techniques, radiation treatment target volumes and doses, as well as the use of androgen deprivation therapy.
DOI: 10.1016/j.radonc.2019.05.016
ISSN: 0167-8140
Publicaton type: Journal Article
Keywords: Radiotherapy
Appears in Collections:Oncology / Cancer

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